Personal Genome Diagnostics CE Marks Liquid Biopsy Test

Personal Genome Diagnostics Inc. (PGDx), a leader in cancer genomics, today announced that it has applied the CE mark to PGDx elio™ plasma resolve. It is the first kitted plasma-based NGS oncology test to have that certification, enabling greater access to genomic testing for cancer patients in Europe.

PGDx elio™ plasma resolve is a qualitative in vitro diagnostic test that uses targeted high throughput, parallel-sequencing technology to detect single nucleotide variants (SNVs), small insertion/deletions (indels), amplifications, rearrangements, and microsatellite instability (MSI) in a broad multi-gene panel in circulating cell-free DNA (cfDNA) isolated from plasma samples. It encompasses several clinically actionable variants across tumor types, enabling more informed treatment decisions.

“We are extremely proud of this important milestone,” said Doug Ward, Chief Executive Officer. “Our vision is to improve clinical insight, speed of results, and health economics by delivering a portfolio of regulated tissue-based and liquid biopsy genomic products to laboratories worldwide. The CE mark of PGDx elio™ plasma resolve allows us to bring this product to Europe, providing greater access to patients who could benefit from genomic testing, particularly those who cannot provide tissue samples.”

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Veradigm™ Strengthens its Health Plan and Analytics Solutions by Finalizing Partnership with Pulse8

Veradigm™, an Allscripts (NASDAQ:MDRX), business unit, announced today that it has strengthened its strategic relationship with Pulse8, a leader in healthcare analytics and technology company.

Pulse8 is the first, and only with a patent pending, healthcare analytics and technology company delivering a complete enterprise platform to provide visibility into the efficacy of Risk Adjustment, Quality Improvement, and Pharmacy Management programs. Pulse8 enables both health plans and at-risk providers to achieve precise risk and quality scores in the Medicare Advantage, Managed Medicaid, and ACA Commercial markets as well as with Value-Based Payment models for Medicare. Pulse8’s Illumin8™ Active Intelligence™ platform offers a suite of uniquely pragmatic solutions that are powered by patent-pending Dynamic Intervention Planning to deliver cost-effective and appropriate interventions for closing gaps in documentation, coding, and quality.

Pulse8 strengthens Veradigm’s existing health plan product suite that delivers tools and services to help control costs while optimizing health outcomes for health plan members. The newly combined offering of clinical data exchange solutions, cutting-edge analytics, and point-of-care engagement tools supports Veradigm’s commitment to health plans and health care providers in their drive towards quality outcomes while maximizing return on investment.

“The type of analytics, technology capabilities, and market knowledge that Pulse8 brings to our team complements and strengthens Veradigm’s existing health plan portfolio. John Criswell, CEO, Pulse8, will be responsible for leading our combined efforts,” said Tom Langan, CEO of Veradigm. “The move reflects our strategy to extend and enhance existing solutions in bold new ways to improve healthcare quality, risk score accuracy, and healthcare cost reduction.”

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RackTop Systems Secures $15 Million in Series A Funding

Leading provider of a secure, high-performance Network-Attached Storage (NAS) platform continues aggressive growth, helping federal and commercial organizations solve their most difficult data, cyber security and compliance challenges RackTop Systems, the pioneer of CyberConverged [TM] data security, a new market that fuses data storage with advanced security and compliance into a single platform, today announced it has closed $15 million in Series A funding. The financing was led by Razor’s Edge Ventures and Grotech Ventures with participation from Maryland Venture Fund, Blu Venture Investors and Gula Tech Adventures.

The Series A funding round will enable RackTop to accelerate near-term sales channel and product development expansion. RackTop’s secure, high-performance Network-Attached Storage (NAS) platform with embedded access controls, encryption and compliance has been proven to optimize business operations, improve productivity, reduce cost and strengthen security. RackTop’s technology has been deployed worldwide to manage more than 50 petabytes of customer data in a variety of industries including: the public sector; media, advertising and entertainment; financial services; health care; and life sciences.

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Executive Spotlight—CEO Farzad Mostashari says Aledade supports the doctors ‘doing God’s work’

Farzad Mostashari, M.D., is back near the frontlines of medicine.

After spending a chunk of his career creating policy in Washington, D.C., Mostashari is now running Aledade, the company he co-founded in 2014 to help independent physician practices transition to value-based models.

It’s work he believes in. And it’s not so much being a physician that helps him understand what practices face.

“To me, it’s more our spirit of service of going and seeing that the primary care doctors in rural Arkansas are just doing God’s work,” he said. “They know their patients. They are so connected to their communities. It’s just humbling to be able to support them. I think that’s the key thing—having the spirit of humility and service rather than a [medical] degree.”

Aledade is helping practices stay independent by bringing them together into accountable care organizations (ACOs). Mostashari thinks it’s a model that can help solve some of the healthcare system’s biggest problems by improving the quality of patient care and reducing costs.

Read more here.

On-Demand Home Renovation Leader Curbio Inc. Continues National Expansion with Houston Launch

Curbio Inc., the pre-sale home renovation specialist that’s rapidly expanding from coast-to-coast, has commenced operations in Houston. Headquartered in Maryland, the company’s other markets include Washington, Baltimore, Philadelphia, and Dallas. Service will be rolled out in Atlanta, Phoenix, and Los Angeles over the next three months.

Curbio uses an array of technology and unique processes to deliver on-demand pre-sale home renovation to realtors and their sellers. Innovations such as same-day estimates, real-time video updates, and virtual walkthroughs enable the company to complete projects faster than traditional home improvement companies, resulting in quicker sales and greater proceeds for sellers. Curbio’s one-of-a-kind “renovate now, pay when you sell” financial model defers payment for renovations until the home is sold, with no deposit or finance charges, and no deadline to sell the home and pay for the work.

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Graybug Vision Appoints Frédéric Guerard as Chief Executive Officer

Graybug Vision, Inc., a clinical stage pharmaceutical company developing potentially transformative therapies for ocular diseases, today announced that the Board of Directors has appointed Frédéric Guerard as Chief Executive Officer.

Mr. Guerard’s career in the pharmaceutical industry spans over 20 years and includes multiple leadership, strategic, and commercial roles. He joins from Novartis, where he was previously Worldwide Business Franchise Head of Ophthalmology. In this role, he successfully led the integration of Novartis retina and Alcon pharmaceuticals, and accelerated the rejuvenation of the product pipeline through strategic acquisitions and licensing transactions in dry-eye, presbyopia, and inherited retinal diseases. Prior to this role, he served as Global Franchise Head of Pharmaceuticals at Alcon. He has also held multiple leadership positions at Novartis, including Head of United Kingdom and Ireland, Head and Country President of Australia and New Zealand, Head of Marketing and Sales for Emerging Growth Markets Region, Head and Country President Egypt, and Cluster Head North and West Africa. He has served on the Board of the Association of the British Pharmaceutical Industry (ABPI) and on the Board of Medicines Australia. Mr. Guerard holds a PharmD and a Master of Biological and Medical Sciences from the University of Rouen, France and a Master of Marketing from HEC Paris.

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Graybug Vision Presents Top Line Results of Phase 1/2a ADAGIO Study at Hawaiian Eye & Retina 2019

Graybug Vision, Inc., a clinical stage pharmaceutical company developing potentially transformative therapies for ocular diseases, today announced positive top line results for the ADAGIO study, a Phase 1/2a study of intravitreal GB-102 (sunitinib malate) in patients with wet age-related macular degeneration (AMD), the leading cause of blindness in the developed world for people age 50 and older. These data were presented by David S. Boyer, M.D., of Retina Vitreous Associates, Beverly Hills, CA, during a presentation of “New Developments in Drug Therapy for Retinal Disorders” at the 2019 Hawaiian Eye & Retina annual meeting in Kona, Hawaii.

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Xometry Simplifies Custom Manufacturing Supply Chain, Launches Xometry Supplies

Xometry, the largest online marketplace for custom manufacturing, announced today the launch of Xometry Supplies. Xometry will help its 2,500 manufacturing partners simplify their supply chain by providing relevant materials, tools and industrial supplies when they accept jobs.

“Xometry Supplies is a natural extension of our efforts to provide our partners with both jobs and lower prices for their materials and tools,” said Xometry’s Co-Founder and CEO Randy Altschuler. “Ultimately our AI-driven algorithms will offer what our partners need when they need it, helping reduce not only cost but lead time. We will use these algorithms to make it easier and faster for manufacturers to get competitive pricing and fast delivery from one place, so they can focus on making high quality parts for customers.”

To support this new business line, Xometry has established a materials logistics hub in Lexington, KY and acquired Machine Tool & Supply of Jackson, TN, a leading regional tool supplier with 30+ years of operational experience to accelerate its go-to market effort for tooling and industrial supplies.

Read more here.

Pre-Sale Home Renovation Company Curbio Inc. Furthers Nationwide Expansion with Atlanta Launch

Curbio Inc., a rapidly expanding company that specializes in pre-sale home renovations, today announced that it will begin operations in the Atlanta metro area in February. The Maryland-based company will host a launch party for journalists and top producing listing agents at the rooftop of Atlanta’s Hotel Clermont from 4:30-6:30 pm on Thursday, January 17th.

Curbio focuses exclusively on preparing homes to be listed for sale. A full-service home improvement specialist, the company offers the complete spectrum of interior and exterior services. Venture-capital backed Curbio’s unique “Renovate Now, Pay When You Sell” model simplifies home selling by deferring all renovation costs until settlement.

“Everyone at Curbio is thrilled to have the opportunity to partner with Atlanta realtors to grow their businesses and deliver maximum ROI to their sellers,” said Rick Rudman, Curbio’s president and CEO. “As in the other markets we serve, Curbio looks forward to bringing hassle-free pre-sale home renovation to Atlanta realtors and their clients.”

Read more here.

How Tech Is Easing Returns for Retailers

Now that holiday gifts have been bought, given and received, retailers brace themselves for returns. It’s turning into a big problem, as many returned items never make it back to store shelves but to landfill. A number of companies are developing tech to tackle the issue. Bloomberg’s Emma Chandra speaks with Tobin Moore, chief executive officer of Optoro.

Watch the interview here.