Executive Spotlight—CEO Farzad Mostashari says Aledade supports the doctors ‘doing God’s work’

Farzad Mostashari, M.D., is back near the frontlines of medicine.

After spending a chunk of his career creating policy in Washington, D.C., Mostashari is now running Aledade, the company he co-founded in 2014 to help independent physician practices transition to value-based models.

It’s work he believes in. And it’s not so much being a physician that helps him understand what practices face.

“To me, it’s more our spirit of service of going and seeing that the primary care doctors in rural Arkansas are just doing God’s work,” he said. “They know their patients. They are so connected to their communities. It’s just humbling to be able to support them. I think that’s the key thing—having the spirit of humility and service rather than a [medical] degree.”

Aledade is helping practices stay independent by bringing them together into accountable care organizations (ACOs). Mostashari thinks it’s a model that can help solve some of the healthcare system’s biggest problems by improving the quality of patient care and reducing costs.

Read more here.


On-Demand Home Renovation Leader Curbio Inc. Continues National Expansion with Houston Launch

Curbio Inc., the pre-sale home renovation specialist that’s rapidly expanding from coast-to-coast, has commenced operations in Houston. Headquartered in Maryland, the company’s other markets include Washington, Baltimore, Philadelphia, and Dallas. Service will be rolled out in Atlanta, Phoenix, and Los Angeles over the next three months.

Curbio uses an array of technology and unique processes to deliver on-demand pre-sale home renovation to realtors and their sellers. Innovations such as same-day estimates, real-time video updates, and virtual walkthroughs enable the company to complete projects faster than traditional home improvement companies, resulting in quicker sales and greater proceeds for sellers. Curbio’s one-of-a-kind “renovate now, pay when you sell” financial model defers payment for renovations until the home is sold, with no deposit or finance charges, and no deadline to sell the home and pay for the work.

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Graybug Vision Appoints Frédéric Guerard as Chief Executive Officer

Graybug Vision, Inc., a clinical stage pharmaceutical company developing potentially transformative therapies for ocular diseases, today announced that the Board of Directors has appointed Frédéric Guerard as Chief Executive Officer.

Mr. Guerard’s career in the pharmaceutical industry spans over 20 years and includes multiple leadership, strategic, and commercial roles. He joins from Novartis, where he was previously Worldwide Business Franchise Head of Ophthalmology. In this role, he successfully led the integration of Novartis retina and Alcon pharmaceuticals, and accelerated the rejuvenation of the product pipeline through strategic acquisitions and licensing transactions in dry-eye, presbyopia, and inherited retinal diseases. Prior to this role, he served as Global Franchise Head of Pharmaceuticals at Alcon. He has also held multiple leadership positions at Novartis, including Head of United Kingdom and Ireland, Head and Country President of Australia and New Zealand, Head of Marketing and Sales for Emerging Growth Markets Region, Head and Country President Egypt, and Cluster Head North and West Africa. He has served on the Board of the Association of the British Pharmaceutical Industry (ABPI) and on the Board of Medicines Australia. Mr. Guerard holds a PharmD and a Master of Biological and Medical Sciences from the University of Rouen, France and a Master of Marketing from HEC Paris.

Read more here.


Graybug Vision Presents Top Line Results of Phase 1/2a ADAGIO Study at Hawaiian Eye & Retina 2019

Graybug Vision, Inc., a clinical stage pharmaceutical company developing potentially transformative therapies for ocular diseases, today announced positive top line results for the ADAGIO study, a Phase 1/2a study of intravitreal GB-102 (sunitinib malate) in patients with wet age-related macular degeneration (AMD), the leading cause of blindness in the developed world for people age 50 and older. These data were presented by David S. Boyer, M.D., of Retina Vitreous Associates, Beverly Hills, CA, during a presentation of “New Developments in Drug Therapy for Retinal Disorders” at the 2019 Hawaiian Eye & Retina annual meeting in Kona, Hawaii.

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Xometry Simplifies Custom Manufacturing Supply Chain, Launches Xometry Supplies

Xometry, the largest online marketplace for custom manufacturing, announced today the launch of Xometry Supplies. Xometry will help its 2,500 manufacturing partners simplify their supply chain by providing relevant materials, tools and industrial supplies when they accept jobs.

“Xometry Supplies is a natural extension of our efforts to provide our partners with both jobs and lower prices for their materials and tools,” said Xometry’s Co-Founder and CEO Randy Altschuler. “Ultimately our AI-driven algorithms will offer what our partners need when they need it, helping reduce not only cost but lead time. We will use these algorithms to make it easier and faster for manufacturers to get competitive pricing and fast delivery from one place, so they can focus on making high quality parts for customers.”

To support this new business line, Xometry has established a materials logistics hub in Lexington, KY and acquired Machine Tool & Supply of Jackson, TN, a leading regional tool supplier with 30+ years of operational experience to accelerate its go-to market effort for tooling and industrial supplies.

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Pre-Sale Home Renovation Company Curbio Inc. Furthers Nationwide Expansion with Atlanta Launch

Curbio Inc., a rapidly expanding company that specializes in pre-sale home renovations, today announced that it will begin operations in the Atlanta metro area in February. The Maryland-based company will host a launch party for journalists and top producing listing agents at the rooftop of Atlanta’s Hotel Clermont from 4:30-6:30 pm on Thursday, January 17th.

Curbio focuses exclusively on preparing homes to be listed for sale. A full-service home improvement specialist, the company offers the complete spectrum of interior and exterior services. Venture-capital backed Curbio’s unique “Renovate Now, Pay When You Sell” model simplifies home selling by deferring all renovation costs until settlement.

“Everyone at Curbio is thrilled to have the opportunity to partner with Atlanta realtors to grow their businesses and deliver maximum ROI to their sellers,” said Rick Rudman, Curbio’s president and CEO. “As in the other markets we serve, Curbio looks forward to bringing hassle-free pre-sale home renovation to Atlanta realtors and their clients.”

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How Tech Is Easing Returns for Retailers

Now that holiday gifts have been bought, given and received, retailers brace themselves for returns. It’s turning into a big problem, as many returned items never make it back to store shelves but to landfill. A number of companies are developing tech to tackle the issue. Bloomberg’s Emma Chandra speaks with Tobin Moore, chief executive officer of Optoro.

Watch the interview here.


Personal Genome Diagnostics and KingMed Enter Strategic Partnership to make Comprehensive Genomic Tissue Panel with TMB available in China and Hong Kong

Personal Genome Diagnostics Inc. (PGDx), a leader in cancer genomics, and KingMed Diagnostics, a laboratory services leader in China, announced today that they have entered into a strategic partnership for the PGDx elioTM tissue complete assay. KingMed Diagnostics brings substantial patient reach, encompassing 37 laboratories covering more than 21,000 hospitals and clinics. This partnership provides PGDx and KingMed Diagnostics the opportunity to serve the clinical trial screening needs of pharmaceutical partners in the Asian market through testing sites in mainland China and Hong Kong. In time and as a result of contributing data from these studies, the partners expect to also serve the clinical testing needs of patients and
physicians in those geographies upon the appropriate regulatory approvals of the PGDx elioTM assays.

The PGDx elio™ tissue complete panel is a 500+ gene test for somatic alterations that detects single nucleotide variants (SNVs), small insertion/deletions (indels), amplifications, rearrangements, microsatellite instability (MSI) and tumor mutational burden (TMB). The use of TMB and MSI for the identification of cancer patients whose tumors may be likely to respond to immune checkpoint inhibitor therapy has recently been investigated in clinical trials (TMB) and approved (MSI) by the U.S. Food and Drug Administration (FDA).

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Blue Cross, Aledade team up to support independent practices in North Carolina through ACOs

A health plan and a startup company are pairing up to support independent primary care physicians in North Carolina.

Blue Cross and Blue Shield of North Carolina and Aledade, a well-funded startup that partners with primary care physicians to build and lead accountable care organizations (ACOs), are joining to launch a new initiative that will support hundreds of independently owned and operated primary care physician clinics in the state, according to an announcement Wednesday.

Doctors will be encouraged to join ACOs through which they can earn enhanced reimbursement rates and share in a portion of cost savings generated from the improved quality of care, the two organizations said.

Read more here.